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      "target": "1000324093",
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      "source": "1000324093",
      "target": "1000324101",
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      "source": "1000324096",
      "target": "1000324123",
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    {
      "label": "Article",
      "id": "1000324096",
      "article": {
        "id": "1000324096",
        "date": "2012-09-30T16:00:00.000+00:00",
        "pubMedUrl": "https://pubmed.ncbi.nlm.nih.gov/22066836/",
        "scholarBoostUrl": "http://10.42.2.40/ScholarBoostWeb/#/1000324096",
        "crossrefUrl": null,
        "googleScholarUrl": null,
        "title": "Effect of dilution temperature on boar semen quality",
        "type": null,
        "pmid": "22066836",
        "doi": "https://doi.org/10.1111/j.1439-0531.2011.01938.x",
        "summary": "As boar semen is very sensitive to cold shock and changes in temperature during semen processing can have a profound impact on semen quality, the effect of the extender temperature at the time of dilution was investigated in a two-step dilution protocol for boar semen being processed for liquid storage. Fifteen boars of different breeds and ages from a commercial artificial insemination centre were included. One ejaculate per boar was collected and processed with Beltsville Thawing Solution semen extender. Each ejaculate was diluted (1 : 1) at 30 °C, and subsequently, the samples were diluted (30 × 10(6) sperm/ml) with either preheated extender [29.3 °C ± 0.2 °C, group A (GA)] or extender at room temperature [22.7 °C ± 0.6 °C, group B (GB)]. Samples were transported to the Faculty of Veterinary Medicine (University of Ghent, Belgium) in two isotherm boxes (one per group), stored at 17 °C and investigated for three consecutive days (D0 to D2). At D0, D1 and D2, motility parameters [computer-assisted semen analysis (CASA)] and the per cent of sperm with intact membrane (% IM) by eosin nigrosin staining were evaluated. At D0 and D2, the % of sperm with intact acrosome (% IA) was studied by Pisum sativum agglutinin staining. The average temperature of the 1 : 1 dilution was 29.4 °C ± 1.1 °C immediately after extender addition. No significant differences were found between groups for per cent motility [79.3 ± 9.0 for GA and 81.1 ± 9.2 for GB (p = 0.372)], % progressive motility [56.5 ± 13.3 for GA and 58.4 ± 13.8 for GB (p = 0.737)] or any CASA parameter. No differences were found for % IM [85.1 ± 10.7 and 84.5 ± 3.8 for GA and GB, respectively (p = 0.761)] and % IA [72.2 ± 9.4 for GA and 68.3 ± 16.6 for GB (p = 0.792)]. In conclusion, when a two-step dilution is performed, preheating the extender for the second dilution to match the semen temperature did not result in better semen quality compared to a dilution at a moderate room temperature.",
        "contributor": [
          {
            "author": "A López Rodríguez",
            "affiliation": [
              "Department of Reproduction, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium Mediclab, Aalst, Belgium. alfonso.lopezrodriguez@ugent.be"
            ]
          },
          {
            "author": "T Rijsselaere",
            "affiliation": null
          },
          {
            "author": "P Vyt",
            "affiliation": null
          },
          {
            "author": "A Van Soom",
            "affiliation": null
          },
          {
            "author": "D Maes",
            "affiliation": null
          },
          {
            "author": "A López Rodríguez",
            "affiliation": [
              "Department of Reproduction, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium Mediclab, Aalst, Belgium. alfonso.lopezrodriguez@ugent.be"
            ]
          },
          {
            "author": "T Rijsselaere",
            "affiliation": null
          },
          {
            "author": "P Vyt",
            "affiliation": null
          },
          {
            "author": "A Van Soom",
            "affiliation": null
          },
          {
            "author": "D Maes",
            "affiliation": null
          },
          {
            "author": "A López Rodríguez",
            "affiliation": [
              "Department of Reproduction, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium Mediclab, Aalst, Belgium. alfonso.lopezrodriguez@ugent.be"
            ]
          },
          {
            "author": "T Rijsselaere",
            "affiliation": null
          },
          {
            "author": "P Vyt",
            "affiliation": null
          },
          {
            "author": "A Van Soom",
            "affiliation": null
          },
          {
            "author": "D Maes",
            "affiliation": null
          },
          {
            "author": "A López Rodríguez",
            "affiliation": [
              "Department of Reproduction, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium Mediclab, Aalst, Belgium. alfonso.lopezrodriguez@ugent.be"
            ]
          },
          {
            "author": "T Rijsselaere",
            "affiliation": null
          },
          {
            "author": "P Vyt",
            "affiliation": null
          },
          {
            "author": "A Van Soom",
            "affiliation": null
          },
          {
            "author": "D Maes",
            "affiliation": null
          },
          {
            "author": "A López Rodríguez",
            "affiliation": [
              "Department of Reproduction, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium Mediclab, Aalst, Belgium. alfonso.lopezrodriguez@ugent.be"
            ]
          },
          {
            "author": "T Rijsselaere",
            "affiliation": null
          },
          {
            "author": "P Vyt",
            "affiliation": null
          },
          {
            "author": "A Van Soom",
            "affiliation": null
          },
          {
            "author": "D Maes",
            "affiliation": null
          },
          {
            "author": "A López Rodríguez",
            "affiliation": [
              "Department of Reproduction, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium Mediclab, Aalst, Belgium. alfonso.lopezrodriguez@ugent.be"
            ]
          },
          {
            "author": "T Rijsselaere",
            "affiliation": null
          },
          {
            "author": "P Vyt",
            "affiliation": null
          },
          {
            "author": "A Van Soom",
            "affiliation": null
          },
          {
            "author": "D Maes",
            "affiliation": null
          }
        ],
        "journal": null,
        "keyword": null,
        "similar": null,
        "cited": null
      }
    },
    {
      "label": "Article",
      "id": "1000324093",
      "article": {
        "id": "1000324093",
        "date": "2021-11-26T16:00:00.000+00:00",
        "pubMedUrl": "https://pubmed.ncbi.nlm.nih.gov/34941819/",
        "scholarBoostUrl": "http://10.42.2.40/ScholarBoostWeb/#/1000324093",
        "crossrefUrl": null,
        "googleScholarUrl": null,
        "title": "Relevance of the Ejaculate Fraction and Dilution Method on Boar Sperm Quality during Processing and Conservation of Seminal Doses",
        "type": null,
        "pmid": "34941819",
        "doi": "https://doi.org/10.3390/vetsci8120292",
        "summary": "During boar semen processing and distribution, maximizing the work protocols in the laboratories becomes essential for the conservation of seminal doses. One of the recent implementations in the boar studs to improve efficiency has been semi-automatic semen collection systems, which do not allow to discard fractions of the ejaculate. The objective of this work was to evaluate the dilution method and vibrations (simulating delivery transport) effect on sperm quality (motility, viability, morphology, thermo-resistance test) according to the fraction of ejaculate collected. Two different fractions of the ejaculate were obtained [rich fraction (RF); total fractions (TF)] from six boars, and two dilution methods applied [pouring the extender over the semen (control; ES); pouring the semen over the extender (reverse; SE)]. The seminal doses (2000 × 10 sperm/50 mL) were preserved for 5 days. The results showed that the fraction collected affects sperm quality (better total and progressive motility, and faster sperm in TF;  < 0.05) regardless of the dilution method applied. However, these differences diminished after submitting the semen to the thermo-resistance test, with only differences in sperm viability being observed ( < 0.05). When seminal doses were subjected to vibrations, the sperm viability was more affected in the TF than in the RF group ( < 0.05). In conclusion, using the TF ejaculate leads to comparable results to the RF in sperm quality during storage regardless of the dilution method applied. However, the vibrations of seminal doses are more affected in doses prepared with TF than with RF, although more factors should be included to approach the real conditions during transport.",
        "contributor": [
          {
            "author": "Blanca Sebastián-Abad",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain.",
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Blanca Sebastián-Abad",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain.",
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Blanca Sebastián-Abad",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain.",
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Blanca Sebastián-Abad",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain.",
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Blanca Sebastián-Abad",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain.",
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Blanca Sebastián-Abad",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain.",
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Cmno De Los Clementes Sn, GTC Spermatica Reproducción, 30817 Lorca, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus Mare Nostrum, Universidad de Murcia, 30100 Murcia, Spain."
            ]
          }
        ],
        "journal": null,
        "keyword": null,
        "similar": null,
        "cited": null
      }
    },
    {
      "label": "Article",
      "id": "1000324101",
      "article": {
        "id": "1000324101",
        "date": "2022-01-27T16:00:00.000+00:00",
        "pubMedUrl": "https://pubmed.ncbi.nlm.nih.gov/35205077/",
        "scholarBoostUrl": "http://10.42.2.40/ScholarBoostWeb/#/1000324101",
        "crossrefUrl": null,
        "googleScholarUrl": null,
        "title": "Should All Fractions of the Boar Ejaculate Be Prepared for Insemination Rather Than Using the Sperm Rich Only?",
        "type": null,
        "pmid": "35205077",
        "doi": "https://doi.org/10.3390/biology11020210",
        "summary": "Boar ejaculate is released in several well-characterized fractions, differing in terms of sperm concentration, seminal plasma volume, and composition. However, the inclusion of the last part of the ejaculate for artificial insemination (AI) purposes is still under debate due to its controversial effects. Thus, there is a need to study the potential synergistic impact of the different ejaculate fractions. We aimed to evaluate the effect of accumulative ejaculate fractions on sperm conservation, AI performance, and offspring health. Ejaculates ( = 51) were collected and distributed as follows: F1: sperm-rich fraction; F2: sperm-rich + intermediate fractions; F3: sperm-rich + intermediate + poor fractions. Each group was diluted in a commercial extender, packaged in seminal doses (2000 × 10 sperm/60 mL), and stored at ~16 °C. On day 3 of conservation, sperm were analyzed and used for AI ( = 174). High sperm quality was observed after storage without a significant difference between the groups ( > 0.05). Moreover, no differences were obtained for AI performance (pregnancy and farrowing rates, and litter size;  > 0.05) and offspring health (growth and blood analysis;  > 0.05). Conclusively, the presence of all ejaculate fractions within the seminal doses does not impair the reproductive performance, reporting important economic savings according to the economic model included here.",
        "contributor": [
          {
            "author": "Chiara Luongo",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Departamento de Tecnología Agroalimentaria, Universidad Miguel Hernández, 03202 Elche, Spain."
            ]
          },
          {
            "author": "Iván Hernández-Caravaca",
            "affiliation": [
              "Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Facultad Ciencias de la Salud, Campus de Sant Vicent del Raspeig, E-03080 Sant Vicent del Raspeig, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Carmen Matás",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Chiara Luongo",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Departamento de Tecnología Agroalimentaria, Universidad Miguel Hernández, 03202 Elche, Spain."
            ]
          },
          {
            "author": "Iván Hernández-Caravaca",
            "affiliation": [
              "Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Facultad Ciencias de la Salud, Campus de Sant Vicent del Raspeig, E-03080 Sant Vicent del Raspeig, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Carmen Matás",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Chiara Luongo",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Departamento de Tecnología Agroalimentaria, Universidad Miguel Hernández, 03202 Elche, Spain."
            ]
          },
          {
            "author": "Iván Hernández-Caravaca",
            "affiliation": [
              "Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Facultad Ciencias de la Salud, Campus de Sant Vicent del Raspeig, E-03080 Sant Vicent del Raspeig, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Carmen Matás",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Chiara Luongo",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Departamento de Tecnología Agroalimentaria, Universidad Miguel Hernández, 03202 Elche, Spain."
            ]
          },
          {
            "author": "Iván Hernández-Caravaca",
            "affiliation": [
              "Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Facultad Ciencias de la Salud, Campus de Sant Vicent del Raspeig, E-03080 Sant Vicent del Raspeig, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Carmen Matás",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Chiara Luongo",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Departamento de Tecnología Agroalimentaria, Universidad Miguel Hernández, 03202 Elche, Spain."
            ]
          },
          {
            "author": "Iván Hernández-Caravaca",
            "affiliation": [
              "Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Facultad Ciencias de la Salud, Campus de Sant Vicent del Raspeig, E-03080 Sant Vicent del Raspeig, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Carmen Matás",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Chiara Luongo",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain."
            ]
          },
          {
            "author": "Pedro José Llamas-López",
            "affiliation": [
              "Departamento de Tecnología Agroalimentaria, Universidad Miguel Hernández, 03202 Elche, Spain."
            ]
          },
          {
            "author": "Iván Hernández-Caravaca",
            "affiliation": [
              "Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Facultad Ciencias de la Salud, Campus de Sant Vicent del Raspeig, E-03080 Sant Vicent del Raspeig, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Carmen Matás",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          },
          {
            "author": "Francisco Alberto García-Vázquez",
            "affiliation": [
              "Departamento de Fisiología, Facultad de Veterinaria, Campus de Excelencia Mare Nostrum Universidad de Murcia, 30100 Murcia, Spain.",
              "Institute for Biomedical Research of Murcia (IMIB-Arrixaca), 30120 Murcia, Spain."
            ]
          }
        ],
        "journal": null,
        "keyword": null,
        "similar": null,
        "cited": null
      }
    },
    {
      "label": "Article",
      "id": "1000324123",
      "article": {
        "id": "1000324123",
        "date": "2015-11-30T16:00:00.000+00:00",
        "pubMedUrl": "https://pubmed.ncbi.nlm.nih.gov/26580438/",
        "scholarBoostUrl": "http://10.42.2.40/ScholarBoostWeb/#/1000324123",
        "crossrefUrl": null,
        "googleScholarUrl": null,
        "title": "The Usefulness of Selected Physicochemical Indices, Cell Membrane Integrity and Sperm Chromatin Structure in Assessments of Boar Semen Sensitivity",
        "type": null,
        "pmid": "26580438",
        "doi": "https://doi.org/10.5713/ajas.15.0095",
        "summary": "The present work describes experiments undertaken to evaluate the usefulness of selected physicochemical indices of semen, cell membrane integrity and sperm chromatin structure for the assessment of boar semen sensitivity to processes connected with pre-insemination procedures. The experiments were carried out on 30 boars: including 15 regarded as providers of sensitive semen and 15 regarded as providers of semen that is little sensitive to laboratory processing. The selection of boars for both groups was based on sperm morphology analyses, assuming secondary morphological change incidence in spermatozoa as the criterion. Two ejaculates were manually collected from each boar at an interval of 3 to 4 months. The following analyses were carried out for each ejaculate: sperm motility assessment, sperm pH measurement, sperm morphology assessment, sperm chromatin structure evaluation and cell membrane integrity assessment. The analyses were performed three times. Semen storage did not cause an increase in the incidence of secondary morphological changes in the group of boars considered to provide sperm of low sensitivity. On the other hand, with continued storage there was a marked increase in the incidence of spermatozoa with secondary morphological changes in the group of boars regarded as producing more sensitive semen. Ejaculates of group I boars evaluated directly after collection had an approximately 6% smaller share of spermatozoa with undamaged cell membranes than the ejaculates of boars in group II (p≤0.05). In the process of time the percentage of spermatozoa with undamaged cell membranes decreased. The sperm of group I boars was characterised with a lower sperm motility than the semen of group II boars. After 1 hour of storing diluted semen, the sperm motility of boars producing highly sensitive semen was already 4% lower (p≤0.05), and after 24 hours of storage it was 6.33% lower than that of the boars that produced semen with a low sensitivity. Factors that confirm the accuracy of insemination male selection can include a low rate of sperm motility decrease during the storage of diluted semen, low and contained incidence of secondary morphological changes in spermatozoa during semen storage and a high frequency of spermatozoa with undamaged cell membranes.",
        "contributor": [
          {
            "author": "A Wysokińska",
            "affiliation": null
          },
          {
            "author": "S Kondracki",
            "affiliation": null
          },
          {
            "author": "M Iwanina",
            "affiliation": null
          },
          {
            "author": "A Wysokińska",
            "affiliation": null
          },
          {
            "author": "S Kondracki",
            "affiliation": null
          },
          {
            "author": "M Iwanina",
            "affiliation": null
          },
          {
            "author": "A Wysokińska",
            "affiliation": null
          },
          {
            "author": "S Kondracki",
            "affiliation": null
          },
          {
            "author": "M Iwanina",
            "affiliation": null
          },
          {
            "author": "A Wysokińska",
            "affiliation": null
          },
          {
            "author": "S Kondracki",
            "affiliation": null
          },
          {
            "author": "M Iwanina",
            "affiliation": null
          },
          {
            "author": "A Wysokińska",
            "affiliation": null
          },
          {
            "author": "S Kondracki",
            "affiliation": null
          },
          {
            "author": "M Iwanina",
            "affiliation": null
          },
          {
            "author": "A Wysokińska",
            "affiliation": null
          },
          {
            "author": "S Kondracki",
            "affiliation": null
          },
          {
            "author": "M Iwanina",
            "affiliation": null
          }
        ],
        "journal": null,
        "keyword": null,
        "similar": null,
        "cited": null
      }
    },
    {
      "label": "Article",
      "id": "1000324052",
      "article": {
        "id": "1000324052",
        "date": "2021-11-24T16:00:00.000+00:00",
        "pubMedUrl": "https://pubmed.ncbi.nlm.nih.gov/34944150/",
        "scholarBoostUrl": "http://10.42.2.40/ScholarBoostWeb/#/1000324052",
        "crossrefUrl": null,
        "googleScholarUrl": null,
        "title": "Integrity of Sperm Cell Membrane in the Semen of Crossbred and Purebred Boars during Storage at 17 °C: Heterosis Effects",
        "type": null,
        "pmid": "34944150",
        "doi": "https://doi.org/10.3390/ani11123373",
        "summary": "The aim of the study was to assess changes in the integrity of sperm cell membranes during the storage of semen collected from Duroc × Pietrain crossbred boars and purebred boars of the component breeds. To compare the cell membrane integrity of sperm heads in crossbred and purebred boars, heterosis effects were estimated. The study was conducted on 48 ejaculates collected from Duroc × Pietrain crossbred boars and from purebred Duroc and Pietrain boars used for artificial insemination. Microscope slides were prepared from each ejaculate for the evaluation of the cell membrane integrity of the sperm, at 1, 24, 48, 72, and 96 h after collection of the ejaculate. Diluted ejaculates were stored at 17 °C. Sperm membrane integrity was analysed by two methods: SYBR-14/PI and eosin-nigrosin. Our results showed that the cell membrane integrity of sperm heads changed with storage time, but the extent of the changes varied depending on the genetic group of boars. The semen of Duroc × Pietrain crossbreds was clearly seen to be less sensitive to storage conditions than that of boars of the parent breeds, which was confirmed by the calculated heterosis effects. The percentage of sperm with an intact cell membrane was higher in crossbred boars than in purebred boars ( ≤ 0.05). In addition, significantly fewer moribund sperm spermatozoa and spermatozoa with a damaged cell membrane were observed in crossbred boars ( ≤ 0.05). In the semen of purebred Duroc and Pietrain boars, the cell membrane integrity of the sperm should be assessed more often during storage than in the semen of Duroc × Pietrain crossbred boars. This study provides valuable information for the development and implementation of semen quality monitoring in crossbred boars and boars of the parent breeds during storage at 17 °C with respect to the cell membrane structure of sperm heads. The evaluation methods used effectively identify damage to the cell membranes of the sperm during semen storage.",
        "contributor": [
          {
            "author": "Anna Wysokińska",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Dorota Szablicka",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Anna Wysokińska",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Dorota Szablicka",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Anna Wysokińska",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Dorota Szablicka",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Anna Wysokińska",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Dorota Szablicka",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Anna Wysokińska",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Dorota Szablicka",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Anna Wysokińska",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          },
          {
            "author": "Dorota Szablicka",
            "affiliation": [
              "Faculty of Agrobioengineering and Animal Husbandry, Siedlce University of Natural Sciences and Humanities, 08110 Siedlce, Poland."
            ]
          }
        ],
        "journal": null,
        "keyword": null,
        "similar": null,
        "cited": null
      }
    }
  ]
}


import moment from "moment"
const nodes = data.nodes.map(item => {
  // 计算结点三层层级关系，如果存在多级，设置为单独层级
  const leval = { 1: [], 2: [] }
  data.links.forEach(item => { item.source === '1000324096' ? leval[1].push(item.target) : leval[2].push(item.target) })
  // 节点设置
  const { date, contributor, doi } = item.article
  let name = ''
  if (contributor && contributor.length && contributor[0].author) {
    name = contributor[0].author
  }
  let category = 0
  if (leval[1].includes(item.id)) { category = 1 }
  if (leval[2].includes(item.id)) { category = 2 }
  if (leval[1].includes(item.id) && leval[2].includes(item.id)) { category = 'mixed' }
  return {
    id: item.id,
    title: item.article.title,
    name: name + ' , ' + (moment(date).format('YYYY') || item.id),
    date: moment(date).format('YYYY-MM-DD'),
    doi,
    category: category
  }
})


export default {
  links: data.links,
  nodes: nodes
}